By Michelle McGuire, Mark A McGuire, Lars Bode
Prebiotics and Probiotics in Human Milk: Origins and features of Milk-Borne Oligosaccharides and Bacteria offers a accomplished, but approachable, treatise on what's at present recognized in regards to the origins and services of human milk oligosaccharides (HMO), the complicated sugars in milk that aren't digested via the child.
The booklet examines how HMOs and micro organism in human milk may well functionality independently and coordinately to steer either maternal and little one health and wellbeing. Human milk is the one meals “designed in particular to nourish people, certainly representing the essence of an ideal “functional food. And even though researchers were learning its composition for many years, unusually little is absolutely understood in regards to the origins and capabilities of its myriad parts, a space that's very true for HMOs and micro organism.
This e-book presents a radical evaluate of the most recent learn on those inter-related milk ingredients as written by means of a crew of specialists from either academia and who actively behavior HMO and human milk microbiome learn as they pastime to use this new wisdom to child meals. every one bankruptcy offers target reason for what study remains to be wanted during this quickly evolving region, additionally discussing the demanding situations and possibilities confronted through the in including HMO and microbes to child meals products.
This e-book is a helpful source for nutrients researchers keen on little one food, foodstuff scientists and product builders engaged on boy or girl formulation, and clinicians drawn to broadening their realizing of some great benefits of human milk for infants.
- Presents a reader-friendly, highly-curated textual content that features a assessment of the literature with regards to origins, variability, metabolism, and features of HMO and human milk bacteria
- Discusses the capability implications of HMO and milk microbiota to – for example, usage within the dairy and baby formula
- Consists of studying aids, similar to pull rates, serious precis statements, and an in depth record of released literature throughout
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Additional info for Prebiotics and Probiotics in Human Milk. Origins and Functions of Milk-Borne Oligosaccharides and Bacteria
1988. Immunoaffinity isolation of a sialyl-Le(a) oligosaccharide from human milk. Journal of Biochemistry 104, 591–594. , 1989. Three novel oligosaccharides with the sialyl-Lea structure in human milk: isolation by immunoaffinity chromatography. Biochemistry 28, 8891–8897. , 1990. Occurrence of tetra- and pentasaccharides with the sialyl-Le(a) structure in human milk. J. Biol. Chem. 265, 4859–4862. , 1991a. Novel oligosaccharides with the sialyl-Lea structure in human milk. Biochemistry 30, 2869–2876.
1997) on lactose, which is synthesized in a large amount by the action of β4GalT-I and α-lactalbumin, GlcNAcβ1-3Galβ1-4Glc is formed as shown in Fig. 5. , 1997) and iGnT as shown in the left-hand side of Fig. 5. The sugar chains, produced by the concerted action of the two glycosyltransferases, are all neo-type, which has only the repeating structures of the Galβ1-4GlcNAcβ1-3 group. , 1999) instead of β4GalT, extension of the sugar chain might stop there. , 1991) as shown in the right-hand side of Fig.
2012) Aye-Aye (Daubentonia madagascariensis) Milk 1 3-FL 2 2' -FL Fucα1-2Galβ1-4Glc Taufik et al. (2012) 3 LNT Galβ1-3GlcNAcβ1-3Galβ1-4Glc Taufik et al. (2012) 4 LNnT Galβ1-4GlcNAcβ1-3Galβ1-4Glc Taufik et al. (2012) 5 DFL Fucα1-2Galβ1-4Glc 3 Fucα1 Taufik et al. (2012) 6 LNFP II Galβ1-3GlcNAcβ1-3Galβ1-4Glc 4 Fucα1 Taufik et al. (2012) 7 LNFP III Galβ1-4GlcNAcβ1-3Galβ1-4Glc 3 Fucα1 Taufik et al. (2012) 8 LNFP VI Galβ1-4GlcNAcβ1-3Galβ1-4Glc 3 Fucα1 Taufik et al. (2012) 9 LNnH Galβ1-4GlcNAcβ1 Galβ1-4GlcNAcβ1 10 FLNnH 6 Galβ1-4Glc 3 Fucα1 3 Galβ1-4GlcNAcβ1 6 Galβ1-4GlcNAcβ1 Taufik et al.
Prebiotics and Probiotics in Human Milk. Origins and Functions of Milk-Borne Oligosaccharides and Bacteria by Michelle McGuire, Mark A McGuire, Lars Bode