New PDF release: Genome Function, Cell Interactions, and Differentiation

By A.A. Moscona and Alberto Monroy (Eds.)

ISBN-10: 0080584411

ISBN-13: 9780080584416

ISBN-10: 012153118X

ISBN-13: 9780121531188

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1982). Proc. Nutl. Acud. Sci. , in press. Klar, A. J. , and MacLeod, K. (1979). Genetics 93, 37-50. Klar, A. J. , Strathern, J . , and Hicks, J. B. (1980). Cell 22, 291-298. Klar, A. J. , Strathern, J. , Broach, J. , and Hicks, J. B. (1981a). Nature (London) 289, 239-244. Klar, A. J. , Strathern, J. , and Hicks, J. B. (1981b). Cell 25, 517-524. Klar, A. J. , Hicks, J . , and Strathern, J. N. (1982). Cell 28, 551-561. , and Herskowitz, I. (1982). Cell, in press. MacKay, V. , and Manney, T. R. (1974).

1980). Genetics 94, 383-423. Haber, J. , and George, J. P. (1979). Genetics 93, 13-35. , and Oshima, Y. (1974). Genetics 77, 639-650. Hartwell, L. , and Unger, M. W. (1977). J. Cell Biol. 75, 422-435. , and Oshima, Y. (1981). I n “Molecular Biology of the Yeast Succharomyces: Life Cycle and Inheritance” (J. N. Strathern, E. W. Jones, and J. R. ), pp. 181-209. , Cold Spring Harbor, New York. , and Strathern, J. (1980). I n “The Molecular Genetics of Development” (W. Loomis and T. ), pp. 79-118.

Whether these behaviors of sir- mutants reflect alterations of the normal process or superimposing of an unnatural pathway of switching remains to be determined. One additional level of control of the switching process is known: switching occurs in a and a cells but not in a h cells. Because switching 1. CELLULAR DIFFERENTIATION IN YEAST 11 occurs in a/a and a h cells, the block in a/a cells is not due to diploidy per se. , 1979). The basis for the inhibition of switching has recently been determined and is rather simple: the H O gene product is not made in a h cells.

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Genome Function, Cell Interactions, and Differentiation by A.A. Moscona and Alberto Monroy (Eds.)


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