Download PDF by David S. Latchman: Eukaryotic Transcription Factors,

By David S. Latchman

ISBN-10: 0080531261

ISBN-13: 9780080531267

ISBN-10: 0124371787

ISBN-13: 9780124371781

Now in two-colour all through, the fourth version of Eukaryotic Transcription elements has been thoroughly rewritten and restructured take into consideration the super advances in our realizing of transcription elements and the mechanisms during which they act. huge emphasis has been given to the interplay among transcription components and chromatin constitution. additionally integrated is a wholly new part at the mediator complicated and growth of the gap dedicated to co-activators and co-repressors. This publication is vital interpreting for all those that desire to comprehend the influence of molecular biology on medication, no matter what their speciality. * significant households of eukaryotic transcription components defined * Mechanisms of gene activation and repression analysed * Structure-function relationships indicated * interplay among transcription components and chromatin constitution defined * Roles in inducible and mobile type-specific gene expression * Roles in improvement, differentiation and human ailments together with melanoma * tools of analysis in vitro and in vivo

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And Britten, R. J. (1983) Very short repeats and co-ordinate induction of genes. Nature 301, 468–470. , Treacy, M. N. G. (1990) A two-base change in a POU factor binding site switches pituitary-specific to lymphoid-specific gene expression. Genes and Development 4, 43–51. Felsenfeld, G. and Groudine, M. (2003) Controlling the double helix. Nature 421, 448– 453. , Stafford, J. and Queen, C. (1986) Synergism between immunoglobulin enhancers and promoters. Nature 322, 383–385. Goll, M. G. and Bestor, T.

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Eukaryotic Transcription Factors, by David S. Latchman


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