Drinking water and health. Volume 6 - download pdf or read online

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To what extent should reversible effects and common variants be taken into consideration in risk assessment? These questions cannot be answered from a scientific point of view alone but will require public policy decisions that take into account the benefit of the chemicals under consideration and priorities for protecting public health. Decisions at this level will greatly influence the requirements for safety testing and risk assessment. REFERENCES ACS (American Cancer Society). 1980. Cancer Facts & Figures.

REFERENCES ACS (American Cancer Society). 1980. Cancer Facts & Figures. , New York. 31 pp. Anderson, E. S. Environmental Protection Agency). 1983. Quantitative approaches in use to assess cancer risk. Risk Anal. 3:277-295. , and D. Neubert. 1980. Testing for embryotoxicity. Arch. Toxicol. (Suppl. 4):256-266. , D. Oerter, R. Krowke, and H. Spielmann. 1978. Embryonic development and mitochondrial function. III. Inhibition of respiration and ATP generation in rat embryos by thiamphenicol. Teratology 18:93-102.

1977), are often not manifested until adolescence or later. They are usually examined as end points in themselves without correlation to outcomes observable at the time of birth. Observations made at the time of birth indicate that the major effects from prenatal exposure are embryo death, malformations, and growth retardation. The relationship between these outcomes is complex, and varies with the agent, the time of exposure, and the dose. Some developmental toxicants can cause malformations in the entire litter at exposure levels not causing embryo death.

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Drinking water and health. Volume 6 by Unknown

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