By Brenda A. Wilson
*Appears Retail*Discover the techniques bacterial pathogens use to outlive and multiply.
Focuses on center ideas in line with the growing to be knowing of the underlying similarities between pathogens and their mechanisms of motion, and is a prompt textual content for one-semester microbiology courses.
Presents the newest learn to aid scholars discover the mechanisms wherein bacterial pathogens reason infections in people and animals.
Includes new insurance of key findings at the mechanisms of bacterial secretion, pollution, and rules.
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In the mouth, defensins may be the reason why infections of the tongue are so uncommon and why animals lick their wounds. In the crypts of the intestinal mucosa, they are presumably protecting the intestinal stem cells, which divide constantly to replenish the cells of the intestinal mucosa. These peptides probably have some antibacterial effects that protect these locations from bacteria. It is worth keeping in mind, however, that the membrane-disrupting activity of these peptides can be inhibited by physiological salt concentrations and by serum.
The large intestine (colon) harbors an abundant and rich assortment of normal microbiota, the majority (97%) of which are anaerobes or facultative anaerobes. Many of these bacteria use carbohydrates and fats that are not digested by the stomach or absorbed by the small intestine. , vitamin K, vitamin B12, and other B vitamins) and other nutrients that the intestine can absorb. Recent experimental evidence indicates that indigenous bacteria play a crucial inductive role in gut and immune development during early postnatal life.
One of the earliest models for studying skin infections was the burned-rodent model. A patch of skin on an animal that is anesthetized is shaved and then burned with an alcohol flame. Just as is the case with human burns, bacteria that could not infect intact skin can infect the burned rodent tissue. The eye is another surface of the body that is remarkably resistant to infection. Eye infections of the sort seen in patients who have been careless with contact lenses or have suffered small cuts in the cornea are mimicked by a rabbit model in which small, shallow cuts are made in the cornea of the animal’s eye.
Bacterial Pathogenesis: a Molecular Approach by Brenda A. Wilson