By Dennis P. O'Malley (auth.)
The spleen is an organ which has various features together with immunologic and hematologic. The Atlas of Spleen Pathology describes and selectively illustrates the traditional and pathologic stipulations that afflict the spleen. This amazing selection of top of the range electronic photographs will materially relief in carrying on with efforts to acknowledge, comprehend, and adequately interpret the gross and lightweight microscopic findings in spleens.
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Hepatosplenic T-cell lymphoma with preserved white pulp structure (lower left), and increased abnormal lymphocytes in the red pulp. The lymphocytes are slightly polymorphous in appearance. Cells are round to slightly irregular, with mature chromatin and small amounts of cytoplasm Fig. 100 Hepatosplenic T-cell lymphoma. In this example of hepatosplenic T-cell lymphoma, the cells are more intermediate to large in size, with vesicular chromatin. Most cases of hepatosplenic T-cell lymphoma express gamma/delta T-cell receptors 42 3 Lymphoid Neoplasms Fig.
Intermediate magnification of spleen in patient with plasma cell myeloma. There is no histologic evidence of PCM in this spleen. Rather, the spleen is enlarged due to a massive increase in extramedullary hematopoiesis. 7 33 Fig. 67 Hairy cell leukemia. In this low-magnification image of spleen, there is diffuse involvement by a proliferation of small lymphocytes; many of these have increased pale cytoplasm. There are no white pulp structures present, as this is diffuse red pulp involvement. There is some infiltration of the capsule.
45 Follicular lymphoma. In this example of a low-grade follicular lymphoma, the splenic white pulp nodules are variable in size but have a relatively uniform appearance of their cellular components Fig. 43 Follicular lymphoma. Low magnification of follicular lymphoma in the spleen. At this magnification, most B-cell lymphomas that predominantly involve splenic white pulp cannot be reliably distinguished from one another Fig. 46 Follicular lymphoma. Another example of low-grade follicular lymphoma in spleen.
Atlas of Spleen Pathology by Dennis P. O'Malley (auth.)